Regenerative skin treatments (the foundation)
- Best for: Thin, crepey under-eye and brow skin
- Downtime: 1–3 days of mild bumps or swelling
- Lasts: Around 6–12 months with a course
For the very thin skin around the eyes, treatments that improve skin quality and resilience are usually the first line. Polynucleotides (PN) — long-chain DNA fragments from wild salmon, brand example Rejuran® — are understood to act as a “repair signal,” supporting fibroblasts to produce more collagen and elastin, and helping the skin hold moisture. A formulation suited to the delicate skin around the eye is often used here. PDRN is a related compound that supports the skin’s repair processes and is useful in this sensitive area. Multi-ingredient skinboosters such as Profhilo, Sunekos, NCTF, and klardie deliver hyaluronic acid and balanced nutrients to support hydration and quality. PRP and platelet-derived exosomes (both autologous, derived from the patient’s own platelets) can also support tissue quality in this area. Treatment is typically a short course of 2–3 sessions a few weeks apart.









