Polynucleotides and PDRN
- Best for: Thin, finely crinkled skin
- Downtime: 1–3 days of mild bumps
- Lasts: Around 6–12 months with a course
Polynucleotides (PN) such as Rejuran® — long-chain DNA fragments from wild salmon — are understood to act as a “repair signal,” supporting fibroblasts to produce more collagen and elastin and thickening the dermis. PDRN is a related shorter-chain compound. A short course is typical, with results developing over weeks to months.
See full treatment page: Polynucleotides







